The Alaskan senator's vote was the latest example of the independent streak she forged since overcoming a Republican primary challenge in 2010 to win re-election as a rare write-in candidate.
But Murkowski said she is a "no" on the nomination but will "pair" her vote with Daines and be marked "present" instead, meaning that Daines can remain at the wedding and not have to rush back.
With Republicans clinging to a two-vote majority, one Republican voted to stop the nomination, one Democrat to send it further.
Republican Senator Susan Collins and Joe Manchin, a Democrat, both indicated their backing for the judge on Friday, BBC reported. There are only six Republican women in the Senate. Trump's first nominee, Neil Gorsuch, was confirmed to the Supreme Court a year ago after the Senate changed its rules so that a nominee could be confirmed to the high court with a simple majority.
The Senate Judiciary Committee confirmed his nomination on party lines, after which his nomination moved to the Senate floor.
"Christine expressed anger at Mr. Turner's lenient sentence, stating that she particularly was bothered by it because she was assaulted in high school by a man who was now a federal judge in Washington, D.C.", Koegler wrote. Her decision is in stark contrast to the one made earlier today by Sen. Two other women later emerged with sexual misconduct allegations from the 1980s, all of which Kavanaugh has denied.
Death toll from Indonesian natural disaster , tsunami rises to 844
Dozens of people are feared to be underneath the rubble of one hotel alone, the Roa-Roa in the devastated coastal resort of Palu . Palu , a city of 380,000 on the western coast of central Indonesia's Sulawesi island, stood in ruins.
Their support makes Saturday's vote to confirm Kavanaugh an apparent formality after a battle that riveted the nation for almost a month.
In the pivotal moment on Friday, Mrs Collins, perhaps the chamber's most moderate Republican, proclaimed her support for Mr Kavanaugh at the end of a Senate floor speech that lasted almost 45 minutes.
Kavanaugh now has enough support to be confirmed in a vote planned for Saturday afternoon.
"We will be ill-served in the long run if we abandon the presumption of innocence and fairness, tempting though it may be", Collins said in remarks that stretched for more than 40 minutes but addressed the sexual-abuse allegations only near the end.
"He's just an extraordinary person... and I think he's going to make us all very proud", Trump added.
The Senate is likely to vote late Saturday. However, some Republicans were concerned that Flake would change his mind, since he had called for a delay in the vote on Kavanaugh's confirmation to allow the FBI to conduct a brief investigation into the allegations against the judge.