Cormier (21-1-1NC) flattened the UFC's long-reigning heavyweight champ with a right uppercut out of a clinch.
Brock Lesnar entered the Octagon and went after Daniel Cormier after he beat Stipe Miocic to become the second fighter to hold two UFC championships in two divisions at the same time after Conor McGregor.
We see this fight playing out very much like that with Cormier parrying Miocic's punches and keeping him at bay until he ultimately gets a takedown. Cormier and Lesnar are expected to battle for the UFC heavyweight title sometime before the year is out.
'I'm at a point now where it's going to be hard to fight a Curtis Blaydes or a contender at 205, ' Cormier said in the post-fight press conference.
"Now there's a guy who I've known for a long time", he began. Lesnar must be in the pool again for six months before he is allowed to compete again with UFC, so if he has indeed re-entered that testing pool again, his return to UFC is most certainly on.
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But the Real Madrid superstar has been at the heart of much of what went right for Portugal at this World Cup . In football, there are no moral victories and I would have preferred to play worse and win the match.
If Cormier can win and claim two championship belts at the same time, it will be one of the most impressive accomplishments in MMA history.
Cormier has never lost to anyone except Jon Jones, the star-crossed former light heavyweight champion who beat him twice.
The UFC's annual International Fight Week show in its hometown also includes a tantalizing heavyweight matchup between sluggers Derrick Lewis and Francis Ngannou.
Cormier fought extensively at heavyweight earlier in his career.
Welterweight slugger "Platinum" Mike Perry and short-notice replacement Paul "The Irish Dragon" Felder served up an incredible three-round war in their main card bout. The fight must take place in 2018 for the wagers to pay out.
One thing Cormier said did seem to catch Miocic's attention. The deal included Lesnar being allowed to fight in the UFC, which is something he insisted on if he were to re-sign with the pro wrestling giant. Both fighters were covered in Felder's blood by the final bell.