It was a big night for Three Billboards Outside Ebbing, Missouri.
Allison Janney was named best supporting actress in a drama film for her role in I, Tonya - the story of the Olympic figure skater Tonya Harding.
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"Three Billboards Outside Ebbing, Missouri" was the most honored movie, winning four globes, including Best Motion Picture, Drama.
James Franco won the best actor in a comedy award for his turn as the eccentric filmmaker Tommy Wiseau in The Disaster Artist.
But Lady Bird, which took home Best Motion Picture, Comedy or Musical, isn't due to hit screens here until February 15. The top TV victor, "Big Little Lies", also won four awards.
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Google chief Sundar Pichai said "portions of the memo violate our code of conduct and cross the line by advancing harmful gender stereotypes in our workplace".
The evening began with the normally colorful red carpet transformed into a sea of black gowns as actresses showed solidarity with victims of sexual harassment inside and outside the entertainment industry. "We are here for the work".
It has crotch-kicking, Sam Rockwell and enough swearing to make a tradie blush which makes Three Billboards Outside Ebbing, Missouri our new favourite movie.
Mexican director Guillermo del Toro won best director for magical fantasy "The Shape of Water".
Conspicuously absent from the spotlight were any honors for Steven Spielberg's politically charged drama The Post, which is expected to do well at the upcoming Academy Awards, as well as Christopher Nolan's Dunkirk and the controversially categorized thriller Get Out, which was nominated as a comedy.
"I want all the girls watching here, now, to know that a new day is on the horizon", said Winfrey. This is McDormand's sixth Golden Globes nomination having only received a special award from the HFPA for her part in Robert Altman's Short Cuts in 1994.